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A framework to guide selection of chemical alternatives by National Research Council, Division on Earth and Life PDF

By National Research Council, Division on Earth and Life Studies, Board on Environmental Studies and Toxicology, Board on Chemical Sciences and Technology, Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Governme

ISBN-10: 030931013X

ISBN-13: 9780309310130

ISBN-10: 0309310148

ISBN-13: 9780309310147

Traditionally, laws governing chemical use have usually fascinated by wide-spread chemical substances and acute human healthiness results of publicity to them, in addition to their capability to reason melanoma and different antagonistic well-being results. As medical wisdom has multiplied there was an elevated understanding of the mechanisms in which chemical substances might exert destructive results on human well-being, in addition to their results on other  Read more...

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Extra info for A framework to guide selection of chemical alternatives

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Sustainable Production’s Alternatives Assessment Framework (Rossi et al. S. Environmental Protection Agency Design for the Environment program’s Alternatives Assessment framework (EPA 2014c); the United Nations Environment Program Persistent Organic Pollutants Review Committee’s “General guidance on considerations related to alternatives and substitutes for listed persistent organic pollutants and candidate chemicals” (UNEP 2009); the methodology derived from the University of Massachusetts at Lowell’s Toxic Use Reduction Institute’s (TURI) 2006 Five Chemicals Alternatives Assessment study (TURI 2006a); and the Interstate Chemicals Clearinghouse’s (IC2) Safer Alternatives Assessment Wiki (IC2 2014).

In Chapter 12, two examples of how to implement the committee’s thinking are presented in an alternatives analysis of glitazone and decabromodiphenyl ether. Finally, Chapter 13 describes innovation in process and chemical design, including specifics on how to consider properties upfront when developing new chemical entities. Appendix A provides biographic information on the committee. Appendix B accompanies Chapter 6 and provides an overview of how other frameworks considered ecotoxicity. Appendix C describes the visualization tool ToxPi.

This step aligns the committee’s framework with several other frameworks with regard to this concern. In addition, this step is intended to determine whether human health, environmental, and social equity impacts might occur at a place or time other than the point of use of the chemical of concern. This consideration will serve to determine whether additional assessments are required to compare alternatives. IC2, BizNGO, and the German Guide evaluate whether life cycle concerns indicate a need for a more formal life cycle assessment.

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A framework to guide selection of chemical alternatives by National Research Council, Division on Earth and Life Studies, Board on Environmental Studies and Toxicology, Board on Chemical Sciences and Technology, Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Governme


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